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Japanese Society for Palliative Medicine
News Letter No.86
日本緩和医療学会ニューズレター
Feb 2020  86
Journal Watch
緩和ケアに関する論文レビュー
名古屋大学大学院医学系研究科 看護学専攻基礎・臨床看護学講座
佐藤 一樹
対象雑誌:N Engl J Med, Lancet, Lancet Oncol, JAMA, JAMA Intern Med, JAMA Oncol, BMJ, Ann Intern Med, J Clin Oncol, Ann Oncol, Eur J Cancer, Br J Cancer, Cancer

対象期間:2019年9月〜11月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。


【N Engl J Med. 2019; 381(10-22)】
1.新規抗うつ薬 SAGE-217 の大うつ病に対する無作為化比較試験
Gunduz-Bruce H, Silber C, Kaul I, Rothschild AJ, Riesenberg R, Sankoh AJ, et al. Trial of SAGE-217 in Patients with Major Depressive Disorder. N Engl J Med. 2019;381(10):903-11. [PMID: 31483961]
2.医療・健康でのモバイル端末の総説
Sim I. Mobile Devices and Health. N Engl J Med. 2019;381(10):956-68. [PMID: 31483966]
3.がんの疫学
Welch HG, Kramer BS, Black WC. Epidemiologic Signatures in Cancer. N Engl J Med. 2019;381(14):1378-86. [PMID: 31577882]

【Lancet. 2019; 394(10201-10213)】
4.乳がん切除術の麻酔方法による再発リスク:無作為化比較試験
Sessler DI, Pei L, Huang Y, Fleischmann E, Marhofer P, Kurz A, et al. Recurrence of breast cancer afterregional or general anaesthesia: a randomised controlled trial. Lancet. 2019;394(10211):1807-15. [PMID: 31645288]

【Lancet Oncol. 2019;20(9-11)】
5.肺がん臨床試験での患者報告アウトカムとその分析方法のレビュー
Fiero MH, Roydhouse JK, Vallejo J, King-Kallimanis BL, Kluetz PG, Sridhara R. US Food and Drug Administration review of statistical analysis of patient-reported outcomes in lung cancer clinical trials approved between January, 2008, and December, 2017. Lancet Oncol. 2019;20(10):e582-e9. [PMID: 31579004]
6.高所得国7か国の1995年〜2014年のがんの罹患と予後の疫学
Arnold M, Rutherford MJ, Bardot A, Ferlay J, Andersson TM, Myklebust TA, et al. Progress in cancer survival, mortality, and incidence in seven high-income countries 1995-2014 (ICBP SURVMARK-2): a population-based study. Lancet Oncol. 2019;20(11):1493-505. [PMID:31521509]
7.がん終末期の積極治療に対する介入研究の系統的レビュー
Abedini NC, Hechtman RK, Singh AD, Khateeb R, Mann J, Townsend W, et al. Interventions to reduce aggressive care at end of life among patients with cancer: a systematic review. Lancet Oncol. 2019;20(11):e627- e36.[PMID:31674321]

【JAMA. 2019;322(9-20)】
8.オピオイド使用障害の専門治療機関への通院時間の米国での実態(Letter)
Joudrey PJ, Edelman EJ, Wang EA. Drive Times to Opioid Treatment Programs in Urban and Rural Counties in 5 US States. JAMA. 2019;322(13):1310-2. [PMID:31573628]
9.欧州22か国のICUでの終末期医療の1999年から2016年の変化
Sprung CL, Ricou B, Hartog CS, Maia P, Mentzelopoulos SD, Weiss M, et al. Changes in End-of-Life Practices in European Intensive Care Units From 1999 to 2016. JAMA. 2019:1-12. [PMID:31577037]
10.米国の1959年〜2017年の平均余命と死亡率の疫学(Special Communication)
Woolf SH, Schoomaker H. Life Expectancy and Mortality Rates in the United States, 1959-2017. JAMA. 2019;322(20):1996-2016. [PMID:31769830]

【JAMA Intern Med. 2019;179(9-11)】
11.家族へのオピオイド鎮痛薬処方とオピオイド過剰摂取の関連
Khan NF, Bateman BT, Landon JE, Gagne JJ. Association of Opioid Overdose With Opioid Prescriptions to Family Members. JAMA Intern Med. 2019. [PMID:31233088]
12.大麻の薬物依存症に対するナルビキモルスの治療効果の無作為化比較試験
Lintzeris N, Bhardwaj A, Mills L, Dunlop A, Copeland J, McGregor I, et al. Nabiximols for the Treatment of Cannabis Dependence: A Randomized Clinical Trial. JAMA Intern Med. 2019. [PMID:31305874]
13.長期介護施設の入居高齢者が病院から施設に戻る際のケア移行の有害事象
Kapoor A, Field T, Handler S, Fisher K, Saphirak C, Crawford S, et al. Adverse Events in Long-term Care Residents Transitioning From Hospital Back to Nursing Home. JAMA Intern Med. 2019. [PMID:31329223]
14.末期腎不全での無作為化比較試験の対象者の代表性のメタ分析
Smyth B, Haber A, Trongtrakul K, Hawley C, Perkovic V, Woodward M, et al. Representativeness of Randomized Clinical Trial Cohorts in End-stage Kidney Disease: A Meta-analysis. JAMA Intern Med. 2019. [PMID:31282924]
15.透析患者の自己評価による予後予測とケアに関する認識との関連
O'Hare AM, Kurella Tamura M, Lavallee DC, Vig EK, Taylor JS, Hall YN, et al. Assessment of Self-reported Prognostic Expectations of People Undergoing Dialysis: United States Renal Data System Study of Treatment Preferences (USTATE). JAMA Intern Med. 2019. [PMID:31282920]
16.医師に対する個別的なコーチング介入の無作為化比較試験
Dyrbye LN, Shanafelt TD, Gill PR, Satele DV, West CP. Effect of a Professional Coaching Intervention on the Well-being and Distress of Physicians: A Pilot Randomized Clinical Trial. JAMA Intern Med. 2019. [PMID:31380892]
17.骨粗しょう症に対する薬物療法と予後との関連
Cummings SR, Lui LY, Eastell R, Allen IE. Association Between Drug Treatments for Patients With Osteoporosis and Overall Mortality Rates: A Meta-analysis. JAMA Intern Med. 2019. [PMID:31424486]
18.無症候性の尿路感染症の薬物療法の効果と有害事象
Petty LA, Vaughn VM, Flanders SA, Malani AN, Conlon A, Kaye KS, et al. Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients. JAMA Intern Med. 2019. [PMID:31449295]

【JAMA Oncol. 2019;5(9-11)】
19.がん死亡による国や州の損失の米国での推計
Islami F, Miller KD, Siegel RL, Zheng Z, Zhao J, Han X, et al. National and State Estimates of Lost Earnings From Cancer Deaths in the United States. JAMA Oncol. 2019. [PMID:31268465]
20.米国の高齢者でのHIV感染者と非感染者でのがん関連死亡の比較
Coghill AE, Suneja G, Rositch AF, Shiels MS, Engels EA. HIV Infection, Cancer Treatment Regimens, and Cancer Outcomes Among Elderly Adults in the United States. JAMA Oncol. 2019. [PMID:31369037]
21.2011年〜2017年承認の抗がん剤の臨床試験での患者報告アウトカムの使用状況のレビュー(Letter)
Zettler M, Basch E, Nabhan C. Surrogate End Points and Patient-Reported Outcomes for Novel Oncology Drugs Approved Between 2011 and 2017. JAMA Oncol. 2019. [PMID:31268471]
22.小児急性リンパ性白血病の長期サバイバーでの麻酔薬曝露と認知機能の関連
Banerjee P, Rossi MG, Anghelescu DL, Liu W, Breazeale AM, Reddick WE, et al. Association Between Anesthesia Exposure and Neurocognitive and Neuroimaging Outcomes in Long-term Survivors of Childhood Acute Lymphoblastic Leukemia. JAMA Oncol. 2019. [PMID:31219514]
23.2008年〜2018年承認の抗がん剤の臨床試験での人種の代表性
Loree JM, Anand S, Dasari A, Unger JM, Gothwal A, Ellis LM, et al. Disparity of Race Reporting and Representation in Clinical Trials Leading to Cancer Drug Approvals From 2008 to 2018. JAMA Oncol. 2019:e191870. [PMID:31415071]
24.若手腫瘍医の性別や子の有無とカンファレンス参加の関連
Knoll MA, Griffith KA, Jones RD, Jagsi R. Association of Gender and Parenthood With Conference Attendance Among Early Career Oncologists. JAMA Oncol. 2019. [PMID:31318379]
25.NCCNガイドラインでの系統的レビューとメタ分析の再現性の評価
Wayant C, Page MJ, Vassar M. Evaluation of Reproducible Research Practices in Oncology Systematic Reviews With Meta-analyses Referenced by National Comprehensive Cancer Network Guidelines. JAMA Oncol. 2019.[PMID:31486837]
26.オキサリプラチン主体の大腸がん補助化学療法の有効性と末梢神経障害に対する治療期間の無作為化比較試験
Yoshino T, Yamanaka T, Oki E, Kotaka M, Manaka D, Eto T, et al. Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer: The ACHIEVE Phase 3 Randomized Clinical Trial. JAMA Oncol. 2019. [PMID:31513248]
27.肥満乳がん患者での乳がん関連リンパ浮腫に対する自宅での運動療法と食事制限の無作為化比較試験
Schmitz KH, Troxel AB, Dean LT, DeMichele A, Brown JC, Sturgeon K, et al. Effect of Home-Based Exercise and Weight Loss Programs on Breast Cancer-Related Lymphedema Outcomes Among Overweight Breast Cancer Survivors: The WISER Survivor Randomized Clinical Trial. JAMA Oncol. 2019. [PMID:31415063]
28.進行期前立腺がんの臨床試験でのオピオイド使用状況のレビュー
Roydhouse JK, Suzman DL, Menapace LA, Mishra-Kalyani PS, Sridhara R, Blumenthal GM, et al. Global Variation in Opioid Use in Prostate Cancer Trials. JAMA Oncol. 2019:e192971. [PMID:31513232]
29.がん関連アウトカムに対する運動療法の効果や役割に関する総説
Iyengar NM, Jones LW. Development of Exercise as Interception Therapy for Cancer: A Review. JAMA Oncol. 2019. [PMID:31436828]

【BMJ 2019;366(8212-8224)】
30.COPDの予後予測モデルのシステマティックレビュー
Bellou V, Belbasis L, Konstantinidis AK, Tzoulaki I, Evangelou E. Prognostic models for outcome prediction in patients with chronic obstructive pulmonary disease: systematic review and critical appraisal. BMJ. 2019;367:l5358.[PMID: 31585960]

【Ann Intern Med. 2019; 171(5-10)】
31.米国での足関節捻挫のオピオイド処方率(Letter)
Finney FT, Gossett TD, Hu HM, Waljee JF, Brummett CM, Walton DM, et al. Rate of Opioid Prescriptions for Patients With Acute Ankle Sprain. Ann Intern Med. 2019. [PMID: 31284299]
32.認知症患者の BPSD に対する薬物療法・非薬物療法の効果に関するレビューとメタアナリシス
Watt JA, Goodarzi Z, Veroniki AA, Nincic V, Khan PA, Ghassemi M, et al. Comparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia: A Systematic Review and Network Meta-analysis. Ann Intern Med. 2019. [PMID: 31610547]

【J Clin Oncol. 2019;37(25-33)】
33.小児がんの長期サバイバーでの骨密度低下の予測モデル
van Atteveld JE, Pluijm SMF, Ness KK, Hudson MM, Chemaitilly W, Kaste SC, et al. Prediction of Low and Very Low Bone Mineral Density Among Adult Survivors of Childhood Cancer. J Clin Oncol. 2019;37(25):2217-25. [PMID: 31169453]
34.薬物関連顎骨壊死のMASCC/ISOO/ASCO臨床診療ガイドライン
Yarom N, Shapiro CL, Peterson DE, Van Poznak CH, Bohlke K, Ruggiero SL, et al. Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline. J Clin Oncol. 2019;37(25):2270-90. [PMID: 31329513]
35.小児白血病治療後の長期的な感染症リスク
Pelland-Marcotte MC, Pole JD, Hwee J, Sutradhar R, Science M, Nathan PC, et al. Long-Term Risk of Infections After Treatment of Childhood Leukemia: A Population-Based Cohort Study Using Administrative Health Data. J Clin Oncol. 2019;37(29):2651-60. [PMID: 31393747]
36.がん患者でのインフルエンザワクチン接種の有効性
Blanchette PS, Chung H, Pritchard KI, Earle CC, Campitelli MA, Buchan SA, et al. Influenza Vaccine Effectiveness Among Patients With Cancer: A Population-Based Study Using Health Administrative and Laboratory Testing Data From Ontario, Canada. J Clin Oncol. 2019;37(30):2795-804. [PMID: 31465264]
37.がん再発恐怖に対する心理的介入の系統的レビューとメタ分析
Tauber NM, O'Toole MS, Dinkel A, Galica J, Humphris G, Lebel S, et al. Effect of Psychological Intervention on Fear of Cancer Recurrence: A Systematic Review and Meta-Analysis. J Clin Oncol. 2019;37(31):2899-915. [PMID: 31532725]
38.非転移性がん患者での骨粗しょう症治療のASCO臨床診療ガイドライン
Shapiro CL, Van Poznak C, Lacchetti C, Kirshner J, Eastell R, Gagel R, et al. Management of Osteoporosis in Survivors of Adult Cancers With Nonmetastatic Disease: ASCO Clinical Practice Guideline. J Clin Oncol. 2019;37(31):2916-46. [PMID: 31532726]

【Ann Oncol. 2019;30(9-11)】
39.妊娠中の婦人科がんの国際会議によるガイドライン
Amant F, Berveiller P, Boere IA, Cardonick E, Fruscio R, Fumagalli M, et al. Gynecologic cancers in pregnancy: guidelines based on a third international consensus meeting. Ann Oncol. 2019;30(10):1601-12. [PMID:31435648]
40.血液腫瘍の女性患者での妊孕性温存の多職種アプローチの総説
Salama M, Anazodo A, Woodruff TK. Preserving fertility in female patients with hematological malignancies: a multidisciplinary oncofertility approach. Ann Oncol. 2019;30(11):1760-75. [PMID:31418765]

【Eur J Cancer. 2019;118-122】
41.進行期大腸がん患者の栄養評価とがん治療の有害事象や予後との関連
Gallois C, Artru P, Lievre A, Auclin E, Lecomte T, Locher C, et al. Evaluation of two nutritional scores' association with systemic treatment toxicity and survival in metastatic colorectal cancer: an AGEO prospective multicentre study. Eur J Cancer. 2019;119:35-43. [PMID: 31415985]
42.非小細胞肺がん進行期の化学療法後の筋肉量減少の統合的な画像診断radiomicsによる予測
de Jong EEC, Sanders KJC, Deist TM, van Elmpt W, Jochems A, van Timmeren JE, et al. Can radiomics help to predict skeletal muscle response to chemotherapy in stage IV non-small cell lung cancer? Eur J Cancer. 2019;120:107-13. [PMID: 31514107]
43.小児がんでの治療関連死とそのリスク因子
Loeffen EAH, Knops RRG, Boerhof J, Feijen E, Merks JHM, Reedijk AMJ, et al. Treatment-related mortality in children with cancer: Prevalence and risk factors. Eur J Cancer. 2019;121:113-22. [PMID: 31569066]
44.QOLと患者報告アウトカム研究の現状
Bottomley A, Reijneveld JC, Koller M, Flechtner H, Tomaszewski KA, Greimel E, et al. Current state of quality of life and patient-reported outcomes research. Eur J Cancer. 2019;121:55-63. [PMID: 31561134]

【Br J Cancer. 2019;121(6-11)】
45.英国のがん患者の粗死亡率
Wong KF, Lambert PC, Mozumder SI, Broggio J, Rutherford MJ. Conditional crude probabilities of death for English cancer patients. Br J Cancer. 2019;121(10):883-9. [PMID: 31601960]

【Cancer. 2019;125(17-22)】
46.早期乳がんでの化学療法誘発性末梢神経障害の医療者評価と患者評価の一致
Nyrop KA, Deal AM, Reeder-Hayes KE, Shachar SS, Reeve BB, Basch E, et al. Patient-reported and clinician-reported chemotherapy-induced peripheral neuropathy in patients with early breast cancer: Current clinical practice. Cancer. 2019;125(17):2945-54. [PMID: 31090930]
47.頭頚部がん患者の無治療の割合の性差
Park A, Alabaster A, Shen H, Mell LK, Katzel JA. Undertreatment of women with locoregionally advanced head and neck cancer. Cancer. 2019;125(17):3033-9. [PMID: 31090932]
48.乳がん患者の苦痛評価のがん治療前後の推移
Fayanju OM, Yenokyan K, Ren Y, Goldstein BA, Stashko I, Power S, et al. The effect of treatment on patient-reported distress after breast cancer diagnosis. Cancer. 2019;125(17):3040-9. [PMID: 31120575]
49.小児神経膠腫の成人サバイバーの心理社会アウトカム
Ris MD, Leisenring WM, Goodman P, Di C, Noll J, Levy W, et al. Neuropsychological and socioeconomic outcomes in adult survivors of pediatric low-grade glioma. Cancer. 2019;125(17):3050-8. [PMID: 31231797]
50.小児がんの成人サバイバーでの運動療法の心理的な効果
Tonorezos ES, Ford JS, Wang L, Ness KK, Yasui Y, Leisenring W, et al. Impact of exercise on psychological burden in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2019;125(17):3059-67. [PMID: 31067357]
51.がんサバイバーの医療アクセスとQOLの性的嗜好による違い
Boehmer U, Gereige J, Winter M, Ozonoff A. Cancer survivors' access to care and quality of life: Do sexual minorities fare worse than heterosexuals? Cancer. 2019;125(17):3079-85. [PMID: 31106409]
52.前立腺がん患者の不安評価の評価尺度間の変換
Victorson D, Schalet BD, Kundu S, Helfand BT, Novakovic K, Penedo F, et al. Establishing a common metric for self-reported anxiety in patients with prostate cancer: Linking the Memorial Anxiety Scale for Prostate Cancer with PROMIS Anxiety. Cancer. 2019;125(18):3249-58. [PMID: 31090933]
53.進行がん患者と家族の予後認識の一致とホスピス利用の関連
Trevino KM, Prigerson HG, Shen MJ, Tancredi DJ, Xing G, Hoerger M, et al. Association between advanced cancer patient-caregiver agreement regarding prognosis and hospice enrollment. Cancer. 2019;125(18):3259-65. [PMID: 31145833]
54.若年乳がん患者の補助内分泌療法の治療アドヒアランス
Wassermann J, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, et al. Nonadherent behaviors among young women on adjuvant endocrine therapy for breast cancer. Cancer. 2019;125(18):3266-74. [PMID: 31120571]
55.小児がん長期サバイバーの自殺や危険行動
Korhonen LM, Taskinen M, Rantanen M, Erdmann F, Winther JF, Bautz A, et al. Suicides and deaths linked to risky health behavior in childhood cancer patients: A Nordic population-based register study. Cancer. 2019;125(20):3631-8. [PMID: 31287570]
56.小児白血病の成人サバイバーの視覚性短期記憶
Boulet-Craig A, Robaey P, Barlaam F, Laniel J, Oswald V, Jerbi K, et al. Visual short-term memory activation patterns in adult survivors of childhood acute lymphoblastic leukemia. Cancer. 2019;125(20):3639-48. [PMID: 31310324]
57.前立腺がん患者の性関連QOLの治療法での比較
Mullins BT, Basak R, Broughman JR, Chen RC. Patient-reported sexual quality of life after different types of radical prostatectomy and radiotherapy: Analysis of a population-based prospective cohort. Cancer. 2019;125(20):3657-65. [PMID: 31256432]
58.小児がん長期サバイバーの認知機能、精神健康、QOLの人種間比較
Dixon SB, Li N, Yasui Y, Bhatia S, Casillas JN, Gibson TM, et al. Racial and ethnic disparities in neurocognitive, emotional, and quality-of-life outcomes in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2019;125(20):3666-77. [PMID: 31291014]
59.高齢白血病患者のICU入室後の転帰とその要因
Slavin SD, Fenech A, Jankowski AL, Abel GA, Brunner AM, Steensma DP, et al. Outcomes for older adults with acute myeloid leukemia after an intensive care unit admission. Cancer. 2019;125(21):3845-52. [PMID: 31299106]
60.小児がん長期サバイバーの肛門疾患と精神健康の影響
Madenci AL, Dieffenbach BV, Liu Q, Yoneoka D, Knell J, Gibson TM, et al. Late-onset anorectal disease and psychosocial impact in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2019;125(21):3873-81. [PMID: 31322729]
61.強オピオイドの注射薬使用とがん性疼痛治療の認識の医療者調査
Arthur JA, Reddy A, Smith U, Hui D, Park M, Liu D, et al. Practices and perceptions regarding intravenous opioid infusion and cancer pain management. Cancer. 2019;125(21):3882-9. [PMID: 31291011]
62.膵がん治療と支持療法の統合の総説
Moffat GT, Epstein AS, O'Reilly EM. Pancreatic cancer-A disease in need: Optimizing and integrating supportive care. Cancer. 2019;125(22):3927-35. [PMID: 31381149]
63.進行期前立腺がん患者の骨関連イベントと予後の予測因子
Tablazon IL, Howard LE, De Hoedt AM, Aronson WJ, Kane CJ, Amling CL, et al. Predictors of skeletal-related events and mortality in men with metastatic, castration-resistant prostate cancer: Results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Cancer. 2019;125(22):4003-10. [PMID: 31390061]
64.化学療法の医学用語の誤解に対するビデオ教育介入
Pentz RD, Lohani M, Hayban M, Switchenko JM, Dixon MD, DeFeo RJ, Jr., et al. Videos improve patient understanding of misunderstood chemotherapy terminology. Cancer. 2019;125(22):4011-8. [PMID: 31418849]
65.電子カルテデータを用いた外来がん患者の症状と支持療法ニードの実態調査
Garcia SF, Wortman K, Cella D, Wagner LI, Bass M, Kircher S, et al. Implementing electronic health record-integrated screening of patient-reported symptoms and supportive care needs in a comprehensive cancer center. Cancer. 2019;125(22):4059-68. [PMID: 31373682]
66.ASCOガイドライン作成者の開示していない利益相反
Saleh RR, Majeed H, Tibau A, Booth CM, Amir E. Undisclosed financial conflicts of interest among authors of American Society of Clinical Oncology clinical practice guidelines. Cancer. 2019;125(22):4069-75. [PMID: 31355923]
67.米国の多発性骨髄腫の高齢患者でのガイドライン推奨の支持療法のアドヒアランス
Giri S, Zhu W, Wang R, Zeidan A, Podoltsev N, Gore SD, et al. Underutilization of guideline-recommended supportive care among older adults with multiple myeloma in the United States. Cancer. 2019;125(22):4084-95. [PMID: 31381151]
68.リンパ腫患者と家族のがん治療と研究の認識に関する質的研究
Payne JB, Dance KV, Farone M, Phan A, Ho CD, Gutierrez M, et al. Patient and caregiver perceptions of lymphoma care and research opportunities: A qualitative study. Cancer. 2019;125(22):4096-104. [PMID: 31355929]

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