line
Japanese Society for Palliative Medicine
News Letter No.85
日本緩和医療学会ニューズレター
Nov 2019  85
Journal Watch
緩和ケアに関する論文レビュー
名古屋大学大学院医学系研究科 看護学専攻基礎・臨床看護学講座
佐藤 一樹

対象雑誌:N Engl J Med, Lancet, Lancet Oncol, JAMA, JAMA Intern Med, JAMA Oncol, BMJ, Ann Intern Med, J Clin Oncol, Ann Oncol, Eur J Cancer, Br J Cancer, Cancer

対象期間:2019年6月〜8月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。


【N Engl J Med. 2019;380(23-26), 381(1-9)】
1.オピオイド過剰摂取の予防の総説
Babu KM, Brent J, Juurlink DN. Prevention of Opioid Overdose. N Engl J Med. 2019;380(23):2246-55. [PMID: 31167053]
2.医療用麻薬以外の疼痛マネジメントの総説
Finnerup NB. Nonnarcotic Methods of Pain Management. N Engl J Med. 2019;380(25):2440-8. [PMID: 31216399]

【Lancet. 2019;393(10187-10191), 394(10192-10200)】
3.タジキスタンでの緩和ケア(World Report)
Thornton J. Palliative care in Tajikistan. Lancet. 2019;394(10199):624-6. [PMID: 31448728]

【Lancet Oncol. 2019;20(6-8)】
なし

【JAMA. 2019;321(21-24), 322(1-8)】
4.オピオイド鎮痛薬の処方錠数減量や術前服薬指導と術後オピオイド鎮痛薬消費量の関連
Farley KX, Anastasio AT, Kumar A, Premkumar A, Gottschalk MB, Xerogeanes J. Association Between Quantity of Opioids Prescribed After Surgery or Preoperative Opioid Use Education With Opioid Consumption. JAMA. 2019;321(24):2465-7. [PMID:31237629]
5.ICUでの家族面会制限の緩和とせん妄発症の関連
Rosa RG, Falavigna M, da Silva DB, Sganzerla D, Santos MMS, Kochhann R, et al. Effect of Flexible Family Visitation on Delirium Among Patients in the Intensive Care Unit: The ICU Visits Randomized Clinical Trial. JAMA. 2019;322(3):216-28. [PMID:31310297]

【JAMA Intern Med. 2019;179(6-8)】
6.腫瘍医に対するコミュニケーション介入「Serious Illness Care Program」の外来進行期がん患者の希望の把握への効果:クラスター無作為化比較試験
Bernacki R, Paladino J, Neville BA, Hutchings M, Kavanagh J, Geerse OP, et al. Effect of the Serious Illness Care Program in Outpatient Oncology: A Cluster Randomized Clinical Trial. JAMA Intern Med. 2019;179(6):751-9. [PMID:30870563]
7.米国カリフォルニア州での積極的安楽死法制化に対する各病院の対応(Research letter)
Mehta A, Kelley AS. Advance Care Planning Codes-Getting Paid for Quality Care. JAMA Intern Med. 2019;179(6):830-1. [PMID:30855636]

【JAMA Oncol. 2019;5(3-5)】
8.腫瘍医に対するコミュニケーション介入「Serious Illness Care Program」の外来進行期がん患者との会話の診療記録記載への効果:クラスター無作為化比較試験
Paladino J, Bernacki R, Neville BA, Kavanagh J, Miranda SP, Palmor M, et al. Evaluating an Intervention to Improve Communication Between Oncology Clinicians and Patients With Life-Limiting Cancer: A Cluster Randomized Clinical Trial of the Serious Illness Care Program. JAMA Oncol. 2019;5(6):801-9. [PMID:30870556]
9.がん治療と併用可能なホスピスケア利用と終末期の積極治療・医療費との関連
Mor V, Wagner TH, Levy C, Ersek M, Miller SC, Gidwani-Marszowski R, et al. Association of Expanded VA Hospice Care With Aggressive Care and Cost for Veterans With Advanced Lung Cancer. JAMA Oncol. 2019;5(6):810-6. [PMID:30920603]
10.オピオイド鎮痛薬処方規制に伴う非経口オピオイド鎮痛薬処方不足によるオピオイド処方の変化
Haider A, Qian Y, Lu Z, Naqvi S, Zhuang A, Reddy A, et al. Implications of the Parenteral Opioid Shortage for Prescription Patterns and Pain Control Among Hospitalized Patients With Cancer Referred to Palliative Care. JAMA Oncol. 2019;5(6):841-6. [PMID:30896771]
11.緩和的放射線療法中の不必要な毎日の画像検査を削減するための電子カルテ上の指示追加の効果:無作為化比較試験
Sharma S, Guttmann D, Small DS, Rareshide CAL, Jones J, Patel MS, et al. Effect of Introducing a Default Order in the Electronic Medical Record on Unnecessary Daily Imaging During Palliative Radiotherapy for Adults With Cancer: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Oncol. 2019. [PMID:31246224]

【BMJ 2019;365(8201-8205), 366(8206-8211)】
12.ガバペンチノイドと自殺、過剰摂取、外傷、交通事故、犯罪との関連
Molero Y, Larsson H, D'Onofrio BM, Sharp DJ, Fazel S. Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden. BMJ. 2019;365:l2147. [PMID:31189556]

【Ann Intern Med. 2019;170(11-12), 171(1-4)】
13.ヘロイン使用者の治療アクセスの医療保険での比較
Beetham T, Saloner B, Wakeman SE, Gaye M, Barnett ML. Access to Office-Based Buprenorphine Treatment in Areas With High Rates of Opioid-Related Mortality: An Audit Study. Ann Intern Med. 2019;171(1):1-9. [PMID: 31158849]
14.入院患者に対するオピオイド鎮痛薬初回投与の方法と退院後のオピオイド鎮痛薬使用の関連
Donohue JM, Kennedy JN, Seymour CW, Girard TD, Lo-Ciganic WH, Kim CH, et al. Patterns of Opioid Administration Among Opioid-Naive Inpatients and Associations With Postdischarge Opioid Use: A Cohort Study. Ann Intern Med. 2019;171(2):81-90. [PMID: 31207646]

【J Clin Oncol. 2019;37(16-24)】
15.高齢がん患者の死亡前の抗がん剤投与の米国での経年変化
Fang P, Jagsi R, He W, Lei X, Campbell EG, Giordano SH, et al. Rising and Falling Trends in the Use of Chemotherapy and Targeted Therapy Near the End of Life in Older Patients With Cancer. J Clin Oncol. 2019;37(20):1721-31. [PMID:31141431]
16.がん疼痛に対する薬剤療法の組み合わせによる効果の比較:ネットワークメタ分析
Huang R, Jiang L, Cao Y, Liu H, Ping M, Li W, et al. Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis. J Clin Oncol. 2019;37(20):1742-52. [PMID: 30939089]
17.がん疼痛・倦怠感・精神的苦痛の症状緩和ケアに対するがん患者の認識
Smith TG, Troeschel AN, Castro KM, Arora NK, Stein K, Lipscomb J, et al. Perceptions of Patients With Breast and Colon Cancer of the Management of Cancer-Related Pain, Fatigue, and Emotional Distress in Community Oncology. J Clin Oncol. 2019;37(19):1666-76. [PMID:31100037]
18.がん患者偶発的肺塞栓症の治療と予後
Kraaijpoel N, Bleker SM, Meyer G, Mahe I, Munoz A, Bertoletti L, et al. Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With Cancer: An International Prospective Cohort Study. J Clin Oncol. 2019;37(20):1713-20. [PMID:31116676]
19.副腎皮質ステロイド使用による免疫チェックポイント阻害薬の効果への影響
Ricciuti B, Dahlberg SE, Adeni A, Sholl LM, Nishino M, Awad MM. Immune Checkpoint Inhibitor Outcomes for Patients With Non-Small-Cell Lung Cancer Receiving Baseline Corticosteroids for Palliative Versus Nonpalliative Indications. J Clin Oncol. 2019;37(22):1927-34. [PMID:31206316]
20.前立腺がん術後の性的関心と満足度のPROMISによる評価の妥当性
Agochukwu NQ, Wittmann D, Boileau NR, Dunn RL, Montie JE, Kim T, et al. Validity of the Patient-Reported Outcome Measurement Information System (PROMIS) Sexual Interest and Satisfaction Measures in Men Following Radical Prostatectomy. J Clin Oncol. 2019;37(23):2017-27. [PMID:31232671]
21.高齢がん患者の医療費に対する通院時間の影響
Rocque GB, Williams CP, Miller HD, Azuero A, Wheeler SB, Pisu M, et al. Impact of Travel Time on Health Care Costs and Resource Use by Phase of Care for Older Patients With Cancer. J Clin Oncol. 2019;37(22):1935-45. [PMID:31184952]
22.小児がん女性長期サバイバーに対する乳がん検診促進の無作為化比較試験
Oeffinger KC, Ford JS, Moskowitz CS, Chou JF, Henderson TO, Hudson MM, et al. Promoting Breast Cancer Surveillance: The EMPOWER Study, a Randomized Clinical Trial in the Childhood Cancer Survivor Study. J Clin Oncol. 2019;37(24):2131-40. [PMID: 31260642]
23.小児がん女性長期サバイバーの乳がん死亡リスク
Moskowitz CS, Chou JF, Neglia JP, Partridge AH, Howell RM, Diller LR, et al. Mortality After Breast Cancer Among Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2019;37(24):2120-30. [PMID:31260644]

【Ann Oncol. 2019;30(6-8)】
24.静脈血栓塞栓症治療のレビュー
Ay C, Beyer-Westendorf J, Pabinger I. Treatment of cancer-associated venous thromboembolism in the age of direct oral anticoagulants. Ann Oncol. 2019. [PMID:30918939]
25.小児がん長期サバイバーの骨の健康状態と治療のレビュー
Marcucci G, Beltrami G, Tamburini A, Body JJ, Confavreux CB, Hadji P, et al. Bone health in childhood cancer: review of the literature and recommendations for the management of bone health in childhood cancer survivors. Ann Oncol. 2019. [PMID:31111878]
26.がん診断後の経済的負担の評価尺度のレビュー
Witte J, Mehlis K, Surmann B, Lingnau R, Damm O, Greiner W, et al. Methods for measuring financial toxicity after cancer diagnosis and treatment: a systematic review and its implications. Ann Oncol. 2019;30(7):1061-70. [PMID:31046080]
27.11カ国での1970〜2015年の高齢がん患者の予後
Carioli G, Malvezzi M, Bertuccio P, Hashim D, Waxman S, Negri E, et al. Cancer mortality in the elderly in 11 countries worldwide, 1970-2015. Ann Oncol. 2019. [PMID:31147682]
28.欧州での1990〜2015年のがん患者の予後
Bertuccio P, Alicandro G, Malvezzi M, Carioli G, Boffetta P, Levi F, et al. Cancer mortality in Europe in 2015, and an overview of trends since 1990. Ann Oncol. 2019. [PMID:31147719]

【Eur J Cancer. 2019;114-117】
29.高齢者総合的機能評価による高齢がん患者の予後への影響
Orum M, Jensen K, Gregersen M, Meldgaard P, Damsgaard EM. Impact of comprehensive geriatric assessment on short-term mortality in older patients with cancer-a follow-up study. Eur J Cancer. 2019;116:27-34. [PMID: 31163339]

【Br J Cancer. 2019;120(11-12),121(1-5)】
30.大腸がん患者の社会経済的格差と予後の関連
Syriopoulou E, Morris E, Finan PJ, Lambert PC, Rutherford MJ. Understanding the impact of socioeconomic differences in colorectal cancer survival: potential gain in life-years. Br J Cancer. 2019;120(11):1052-8. [PMID: 31040385]
31.前立腺がん患者の心血管イベントリスク
Moustsen IR, Larsen SB, Duun-Henriksen AK, Tjonneland A, Kjaer SK, Brasso K, et al. Risk of cardiovascular events in men treated for prostate cancer compared with prostate cancer-free men. Br J Cancer. 2019;120(11):1067-74. [PMID:31065112]
32.乳がん化学療法後の脱毛予防のための頭皮冷却法の有効性と安全性
Munzone E, Bagnardi V, Campenni G, Mazzocco K, Pagan E, Tramacere A, et al. Preventing chemotherapy-induced alopecia: a prospective clinical trial on the efficacy and safety of a scalp-cooling system in early breast cancer patients treated with anthracyclines. Br J Cancer. 2019;121(4):325-31. [PMID:31303642]
33.乳がん検診で擬陽性の結果であった女性の体験に関する質的研究のレビュー
Long H, Brooks JM, Harvie M, Maxwell A, French DP. How do women experience a false-positive test result from breast screening? A systematic review and thematic synthesis of qualitative studies. Br J Cancer. 2019;121(4):351-8. [PMID:31332283]
34.化学療法時のパクリタキセルの母乳への移行の症例報告(Brief report)
Jackson C, Morris T, Hung N, Hung T. Breast milk paclitaxel excretion following intravenous chemotherapy-a case report. Br J Cancer. 2019;121(5):421-4. [PMID:31363168]

【Cancer. 2019;125(11-16)】
35.高齢乳がん患者のがん診断後のQOLの変化
Euhus DM, Addae JK, Snyder CF, Canner JK. Change in health-related quality of life in older women after diagnosis of a small breast cancer. Cancer. 2019;125(11):1807-14. [PMID:30707774]
36.乳がん患者の治療意思決定への参加のかかりつけ医による評価
Wallner LP, Li Y, McLeod MC, Gargaro J, Kurian AW, Jagsi R, et al. Primary care provider-reported involvement in breast cancer treatment decisions. Cancer. 2019;125(11):1815-22. [PMID:30707774]
37.前立腺がん患者のQOL評価尺度FACT-Pの症状評価の臨床的に意味ある差
Beaumont JL, Butt Z, Li R, Cella D. Meaningful differences and validity for the NCCN/FACT-P Symptom Index: An analysis of the ALSYMPCA data. Cancer. 2019;125(11):1877-85. [PMID:30690719]
38.AYA世代がんサバイバーの雇用や経済への長期的な影響
Ketterl TG, Syrjala KL, Casillas J, Jacobs LA, Palmer SC, McCabe MS, et al. Lasting effects of cancer and its treatment on employment and finances in adolescent and young adult cancer survivors. Cancer. 2019;125(11):1908-17. [PMID:30707763]
39.乳がん患者の長期的な経済的負担の軽減のための推奨
Dean LT, Moss SL, Rollinson SI, Frasso Jaramillo L, Paxton RJ, Owczarzak JT. Patient recommendations for reducing long-lasting economic burden after breast cancer. Cancer. 2019;125(11):1929-40. [PMID:30839106]
40.がん患者の症状に対するヨガの効果のレビュー
Danhauer SC, Addington EL, Cohen L, Sohl SJ, Van Puymbroeck M, Albinati NK, et al. Yoga for symptom management in oncology: A review of the evidence base and future directions for research. Cancer. 2019;125(12):1979-89. [PMID:30933317]
41.新規がん診断患者のがん臨床試験の知識、態度、自己効力感、受容に対する双方向的なビデオ介入
Polite BN, Cipriano-Steffens TM, Liao C, Miller EL, Arndt NL, Hahn EA. Investigation of a multimedia, computer-based approach to improve knowledge, attitudes, self-efficacy, and receptivity to cancer clinical trials among newly diagnosed patients with diverse health literacy skills. Cancer. 2019;125(12):2066-75. [PMID: 30811591]
42.AYA世代がん患者のがん以外の要因による死亡リスク
Anderson C, Lund JL, Weaver MA, Wood WA, Olshan AF, Nichols HB. Noncancer mortality among adolescents and young adults with cancer. Cancer. 2019;125(12):2107-14. [PMID:30892701]
43.がん患者の居住地域が都会か田舎かでの予後の違いのレビュー
Afshar N, English DR, Milne RL. Rural-urban residence and cancer survival in high-income countries: A systematic review. Cancer. 2019. [PMID:30933318]
44.米国のがん患者でのマリファナ使用
Tringale KR, Huynh-Le MP, Salans M, Marshall DC, Shi Y, Hattangadi-Gluth JA. The role of cancer in marijuana and prescription opioid use in the United States: A population-based analysis from 2005 to 2014. Cancer. 2019. [PMID:31006849]
45.非ホジキンリンパ腫サバイバーの長期的な倦怠感
Mounier N, Anthony S, Busson R, Thieblemont C, Ribrag V, Tilly H, et al. Long-term fatigue in survivors of non-Hodgkin lymphoma: The Lymphoma Study Association SIMONAL cross-sectional study. Cancer. 2019. [PMID:30901086]
46.小児・AYA世代がん患者の終末期の積極的医療と予後
Revon-Riviere G, Pauly V, Baumstarck K, Bernard C, Andre N, Gentet JC, et al. High-intensity end-of-life care among children, adolescents, and young adults with cancer who die in the hospital: A population-based study from the French national hospital database. Cancer. 2019. [PMID:30913309]
47.高齢がん患者の死亡前1年間での予防的な薬物療法の実施状況
Morin L, Todd A, Barclay S, Wastesson JW, Fastbom J, Johnell K. Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing? Cancer. 2019. [PMID:30906987]
48.がん患者の意味と目的に焦点をあてた心理社会的介入のレビューとメタ分析
Park CL, Pustejovsky JE, Trevino K, Sherman AC, Esposito C, Berendsen M, et al. Effects of psychosocial interventions on meaning and purpose in adults with cancer: A systematic review and meta-analysis. Cancer. 2019;125(14):2383-93. [PMID:31034600]
49.米国の1987〜2014年の臓器移植レシピエントのがん関連死亡リスク
Noone AM, Pfeiffer RM, Dorgan JF, Magder LS, Bromberg JS, Lynch CF, et al. Cancer-attributable mortality among solid organ transplant recipients in the United States: 1987 through 2014. Cancer. 2019;125(15):2647-55. [PMID:31034602]
50.進行固形がん患者の予後のこの20年での進歩
Pulte D, Weberpals J, Jansen L, Brenner H. Changes in population-level survival for advanced solid malignancies with new treatment options in the second decade of the 21st century. Cancer. 2019;125(15):2656-65. [PMID:31095726]
51.がん患者に対する職業関連のリハビリテーションのクラスター無作為化比較試験
Fauser D, Wienert J, Beinert T, Schmielau J, Biester I, Kruger HU, et al. Work-related medical rehabilitation in patients with cancer-Postrehabilitation results from a cluster-randomized multicenter trial. Cancer. 2019;125(15):2666-74. [PMID:30985930]
52.乳がん診断後の妊孕性に関する体験
Hawkins Bressler L, Mersereau JE, Anderson C, Rodriguez JL, Hodgson ME, Weinberg CR, et al. Fertility-related experiences after breast cancer diagnosis in the Sister and Two Sister Studies. Cancer. 2019;125(15):2675-83. [PMID: 31012960]
53.進行がん患者の予後予測に関する患者、家族、腫瘍医の認識の正確性
Malhotra K, Fenton JJ, Duberstein PR, Epstein RM, Xing G, Tancredi DJ, et al. Prognostic accuracy of patients, caregivers, and oncologists in advanced cancer. Cancer. 2019;125(15):2684-92. [PMID:31034597]
54.患者ナビゲーションプログラムのがん患者に対する有効性と費用対効果のレビュー
Bernardo BM, Zhang X, Beverly Hery CM, Meadows RJ, Paskett ED. The efficacy and cost-effectiveness of patient navigation programs across the cancer continuum: A systematic review. Cancer. 2019;125(16):2747-61. [PMID: 31034604]
55.左心機能と乳がん治療後の心毒性との関連
Demissei BG, Finkelman BS, Hubbard RA, Zhang L, Smith AM, Sheline K, et al. Detailed phenotyping reveals distinct trajectories of cardiovascular function and symptoms with exposure to modern breast cancer therapy. Cancer. 2019;125(16):2762-71. [PMID:31042319]
56.乳がん患者に対するウェアラブル端末による身体活動に対する介入の無作為化比較試験:ACTIVATE試験
Lynch BM, Nguyen NH, Moore MM, Reeves MM, Rosenberg DE, Boyle T, et al. A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: The ACTIVATE Trial. Cancer. 2019;125(16):2846-55. [PMID:31012970]
57.ACTIVATE試験の副次評価項目の結果
Lynch BM, Nguyen NH, Moore MM, Reeves MM, Rosenberg DE, Boyle T, et al. Maintenance of physical activity and sedentary behavior change, and physical activity and sedentary behavior change after an abridged intervention: Secondary outcomes from the ACTIVATE Trial. Cancer. 2019;125(16):2856-60. [PMID:31012968]
58.がん診断後の自殺リスクに対する診断前の心理介入の効果
Klaassen Z, Wallis CJD, Chandrasekar T, Goldberg H, Sayyid RK, Williams SB, et al. Cancer diagnosis and risk of suicide after accounting for prediagnosis psychiatric care: A matched-cohort study of patients with incident solid-organ malignancies. Cancer. 2019;125(16):2886-95. [PMID:31021430]

Close