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Japanese Society for Palliative Medicine
News Letter No.82
日本緩和医療学会ニューズレター
Feb 2019  82
Journal Watch
緩和ケアに関する論文レビュー
名古屋大学大学院医学系研究科 看護学専攻基礎・臨床看護学講座
佐藤 一樹
対象雑誌:N Engl J Med, Lancet, Lancet Oncol, JAMA, JAMA Intern Med, JAMA Oncol, BMJ, Ann Intern Med, J Clin Oncol, Ann Oncol, Eur J Cancer, Br J Cancer, Cancer

対象期間:2018年9月〜11月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。


【N Engl J Med. 2018; 379(10-22)】
1.合成カンナビノイド関連凝固障害の集団発生の報告
Kelkar AH, Smith NA, Martial A, Moole H, Tarantino MD, Roberts JC. An Outbreak of Synthetic Cannabinoid-Associated Coagulopathy in Illinois. N Engl J Med. 2018;379(13):1216-23. [PMID: 30280655]

【Lancet. 2017; 2018;391(10149-10161)】
なし

【Lancet Oncol. 2018;19(9-11)】
2.緩和ケアのエビデンスに関する包括的なレビュー
Kaasa S, Loge JH, Aapro M, Albreht T, Anderson R, Bruera E, et al. Integration of oncology and palliative care: a Lancet Oncology Commission. Lancet Oncol. 2018;19(11):e588-e653. [PMID: 30344075]

【JAMA. 2018;320(9-20)】
3.オピオイド使用障害予防のための処方箋なしでのナロキソン処方制度化後の薬局実態調査(Letter)
Evoy KE, Hill LG, Groff L, Mazin L, Carlson CC, Reveles KR. Naloxone Accessibility Without a Prescriber Encounter Under Standing Orders at Community Pharmacy Chains in Texas. JAMA. 2018;320(18):1934-7. [PMID: 30422186]
4.ガバペンチンとプレガバリンの処方:英国での実態調査(Letter)
Montastruc F, Loo SY, Renoux C. Trends in First Gabapentin and Pregabalin Prescriptions in Primary Care in the United Kingdom, 1993-2017. JAMA. 2018;320(20):2149-51. [PMID: 30480717]

【JAMA Intern Med. 2018;178(9-11)】
5.肺がん健診時の説明と意思決定に関する質的研究
Brenner AT, Malo TL, Margolis M, Elston Lafata J, James S, Vu MB, et al. Evaluating Shared Decision Making for Lung Cancer Screening. JAMA Intern Med. 2018;178(10):1311-6. [PMID: 30105393]
6.慢性腰痛に対する低用量アミトリプチンの有効性に関する無作為化比較試験
Urquhart DM, Wluka AE, van Tulder M, Heritier S, Forbes A, Fong C, et al. Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial. JAMA Intern Med. 2018;178(11):1474-81. [PMID: 30285054]

【JAMA Oncol. 2018;4(9-11)】
7.小児がん長期サバイバーの運動と死亡率の関連
Scott JM, Li N, Liu Q, Yasui Y, Leisenring W, Nathan PC, et al. Association of Exercise With Mortality in Adult Survivors of Childhood Cancer. JAMA Oncol. 2018;4(10):1352-8. [PMID: 29862412]
8.根治可能がん患者の補完療法利用とがん治療拒否や予後との関連
Johnson SB, Park HS, Gross CP, Yu JB. Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers. JAMA Oncol. 2018;4(10):1375-81. [PMID: 30027204]
9.がん診断後の意思決定や医療に対する非医療職の支援員による介入の無作為化比較試験
Patel MI, Sundaram V, Desai M, Periyakoil VS, Kahn JS, Bhattacharya J, et al. Effect of a Lay Health Worker Intervention on Goals-of-Care Documentation and on Health Care Use, Costs, and Satisfaction Among Patients With Cancer: A Randomized Clinical Trial. JAMA Oncol. 2018;4(10):1359-66. [PMID: 30054634]
10.固形がんサバイバーの死亡リスクの長期的な推移
Dood RL, Zhao Y, Armbruster SD, Coleman RL, Tworoger S, Sood AK, et al. Defining Survivorship Trajectories Across Patients With Solid Tumors: An Evidence-Based Approach. JAMA Oncol. 2018;4(11):1519-26. [PMID: 29860375]
11.がんの罹患、死亡、障害生存年数、障害調整生命年:1990〜2016年の国際的疫学データ
Global Burden of Disease Cancer, Collaboration. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2018;4(11):1553-68. [PMID: 29860482]

【BMJ 2018;360(8165-8177)】
12.オピオイド関連死とオピオイド処方歴の関連
Gomes T, Khuu W, Martins D, Tadrous M, Mamdani MM, Paterson JM, et al. Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada. BMJ. 2018;362:k3207. [PMID: 30158106]

【Ann Intern Med. 2018;169(5-10)】
13.医療用マリファナの米国市民の認識
Keyhani S, Steigerwald S, Ishida J, Vali M, Cerda M, Hasin D, et al. Risks and Benefits of Marijuana Use: A National Survey of U.S. Adults. Ann Intern Med. 2018;169(5):282-90. [PMID: 30039154]
14.米国の2016年のガイドライン前後でのオピオイド処方の変化
Bohnert ASB, Guy GP, Jr., Losby JL. Opioid Prescribing in the United States Before and After the Centers for Disease Control and Prevention's 2016 Opioid Guideline. Ann Intern Med. 2018;169(6):367-75. [PMID: 30167651]
15.慢性疼痛患者の自死:米国の2003〜2014年の大規模データ
Petrosky E, Harpaz R, Fowler KA, Bohm MK, Helmick CG, Yuan K, et al. Chronic Pain Among Suicide Decedents, 2003 to 2014: Findings From the National Violent Death Reporting System. Ann Intern Med. 2018;169(7):448-55. [PMID: 30208405]
16.オピオイドとベンゾジアゼピンの重複処方の状況
Carico R, Zhao X, Thorpe CT, Thorpe JM, Sileanu FE, Cashy JP, et al. Receipt of Overlapping Opioid and Benzodiazepine Prescriptions Among Veterans Dually Enrolled in Medicare Part D and the Department of Veterans Affairs: A Cross-sectional Study. Ann Intern Med. 2018;169(9):593-601. [PMID: 30304353]
17.オピオイド使用障害に対するブプレノルフィン漸減療法の総説
Martin SA, Chiodo LM, Bosse JD, Wilson A. The Next Stage of Buprenorphine Care for Opioid Use Disorder. Ann Intern Med. 2018;169(9):628-35. [PMID: 30357262]
18.プレガバリン併用によるオピオイド関連死のリスク増加(Letter)
Gomes T, Greaves S, van den Brink W, Antoniou T, Mamdani MM, Paterson JM, et al. Pregabalin and the Risk for Opioid-Related Death: A Nested Case-Control Study. Ann Intern Med. 2018;169(10):732-4. [PMID: 30140853]

【J Clin Oncol. 2018;36(22-33)】
19.がん患者の心肺機能に対する運動療法の有効性のシステマティックレビュー
Scott JM, Zabor EC, Schwitzer E, Koelwyn GJ, Adams SC, Nilsen TS, et al. Efficacy of Exercise Therapy on Cardiorespiratory Fitness in Patients With Cancer: A Systematic Review and Meta-Analysis. J Clin Oncol. 2018;36(22):2297-305. [PMID: 29894274]
20.高齢がん患者の化学療法時の高齢者総合機能評価:米国臨床腫瘍学会ASCOガイドライン
Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, et al. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology. J Clin Oncol. 2018;36(22):2326-47. [PMID: 29782209]
21.がん患者の心理的苦痛に対するマインドフルネス認知療法の無作為化比較試験:対面型とインターネット利用型と通常ケアの比較
Compen F, Bisseling E, Schellekens M, Donders R, Carlson L, van der Lee M, et al. Face-to-Face and Internet-Based Mindfulness-Based Cognitive Therapy Compared With Treatment as Usual in Reducing Psychological Distress in Patients With Cancer: A Multicenter Randomized Controlled Trial. J Clin Oncol. 2018;36(23):2413-21. [PMID: 29953304]
22.進行がん患者の抑うつに対する簡便な支持的・表出的精神療法Managing Cancer and Living Meaningfully(CALM)の無作為化比較試験
Rodin G, Lo C, Rydall A, Shnall J, Malfitano C, Chiu A, et al. Managing Cancer and Living Meaningfully (CALM): A Randomized Controlled Trial of a Psychological Intervention for Patients With Advanced Cancer. J Clin Oncol. 2018;36(23):2422-32. [PMID: 29958037]
23.第T相臨床試験に参加する進行がん患者の認知機能の評価
Hlubocky FJ, Sachs GA, Larson ER, Nimeiri HS, Cella D, Wroblewski KE, et al. Do Patients With Advanced Cancer Have the Ability to Make Informed Decisions for Participation in Phase I Clinical Trials? J Clin Oncol. 2018;36(24):2483-91. [PMID: 29985748]
24.小児中枢神経系腫瘍の成人サバイバーの機能的自立と社会的自立
Brinkman TM, Ness KK, Li Z, Huang IC, Krull KR, Gajjar A, et al. Attainment of Functional and Social Independence in Adult Survivors of Pediatric CNS Tumors: A Report From the St Jude Lifetime Cohort Study. J Clin Oncol. 2018;36(27):2762-9. [PMID: 30091946]
25.同種造血幹細胞移植患者の終末期の積極治療の実施状況
Johnston EE, Muffly L, Alvarez E, Saynina O, Sanders LM, Bhatia S, et al. End-of-Life Care Intensity in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation: A Population-Level Analysis. J Clin Oncol. 2018;36(30):3023-30. [PMID: 30183467]
26.がん関連の免疫抑制に対する抗菌予防:米国臨床腫瘍学会ASCO・米国感染症学会ISDA臨床実践ガイドラインの更新
Taplitz RA, Kennedy EB, Bow EJ, Crews J, Gleason C, Hawley DK, et al. Antimicrobial Prophylaxis for Adult Patients With Cancer-Related Immunosuppression: ASCO and IDSA Clinical Practice Guideline Update. J Clin Oncol. 2018;36(33):3043-54. [PMID: 30179565]

【Ann Oncol. 2018;29(9-11)】
27.高齢がん患者の総合高齢者評価のアドヒアランス:ベルギーの実態調査
Kenis C, Decoster L, Flamaing J, Debruyne PR, De Groof I, Focan C, et al. Adherence to geriatric assessment-based recommendations in older patients with cancer: a multicenter prospective cohort study in Belgium. Ann Oncol. 2018;29(9):1987-94. [PMID: 29905766]
28.腫瘍医のコミュニケーション研修:欧州コンセンサス会議からのposition paper
Stiefel F, Kiss A, Salmon P, Peters S, Razavi D, Cervantes A, et al. Training in communication of oncology clinicians: a position paper based on the third consensus meeting among European experts in 2018. Ann Oncol. 2018;29(10):2033-6. [PMID: 30412225]

【Eur J Cancer. 2018;100-104】
29.総合高齢者評価を用いた高齢がん患者の早期死亡の予測モデル
Boulahssass R, Gonfrier S, Ferrero JM, Sanchez M, Mari V, Moranne O, et al. Predicting early death in older adults with cancer. Eur J Cancer. 2018;100:65-74. [PMID: 30014882]
30.欧州でのがんに関する研究のマッピング
Begum M, Lewison G, Lawler M, Sullivan R. Mapping the European cancer research landscape: An evidence base for national and Pan-European research and funding. Eur J Cancer. 2018;100:75-84. [PMID: 30014883]
31.早期乳がん患者の診断後1年間の症状の推移
Davis LE, Bubis LD, Mahar AL, Li Q, Sussman J, Moody L, et al. Patient-reported symptoms after breast cancer diagnosis and treatment: A retrospective cohort study. Eur J Cancer. 2018;101:1-11. [PMID: 30014970]
32.アロマターゼ阻害薬を服薬する乳がん患者での倦怠感の発症率とリスク因子
Mao H, Bao T, Shen X, Li Q, Seluzicki C, Im EO, et al. Prevalence and risk factors for fatigue among breast cancer survivors on aromatase inhibitors. Eur J Cancer. 2018;101:47-54. [PMID: 30014974]
33.悪性黒色腫でのQOL評価尺度EORTC QLQ-C30の臨床的に意味ある最小の差
Musoro JZ, Bottomley A, Coens C, Eggermont AM, King MT, Cocks K, et al. Interpreting European Organisation for Research and Treatment for Cancer Quality of life Questionnaire core 30 scores as minimally importantly different for patients with malignant melanoma. Eur J Cancer. 2018;104:169-81. [PMID: 30359910]

【Br J Cancer. 2018;119(6-10)】
34.根治不能がん患者でのアドバンス・ケア・プラニング介入の無作為化比較試験
Johnson SB, Butow PN, Bell ML, Detering K, Clayton JM, Silvester W, et al. A randomised controlled trial of an advance care planning intervention for patients with incurable cancer. Br J Cancer. 2018;119(10):1182-90. [PMID: 30369600]

【Cancer. 2018;124(17-22)】
35.小児がん長期サバイバーの肥満とステロイド使用歴は関連しない
Belle FN, Kasteler R, Schindera C, Bochud M, Ammann RA, von der Weid NX, et al. No evidence of overweight in long-term survivors of childhood cancer after glucocorticoid treatment. Cancer. 2018;124(17):3576-85. [PMID: 30119140]
36.小児中枢神経系腫瘍の成人サバイバーの社会的適応
Schulte F, Brinkman TM, Li C, Fay-McClymont T, Srivastava DK, Ness KK, et al. Social adjustment in adolescent survivors of pediatric central nervous system tumors: A report from the Childhood Cancer Survivor Study. Cancer. 2018;124(17):3596-608. [PMID: 30067866]
37.がん患者の病期に対する楽観的・現実的・悲観的認識とQOLや予後との関連
de Rooij BH, Thong MSY, van Roij J, Bonhof CS, Husson O, Ezendam NPM. Optimistic, realistic, and pessimistic illness perceptions; quality of life; and survival among 2457 cancer survivors: the population-based PROFILES registry. Cancer. 2018;124(17):3609-17. [PMID: 30192384]
38.乳がん診断後の経済面へのケアの実践状況
Jagsi R, Ward KC, Abrahamse PH, Wallner LP, Kurian AW, Hamilton AS, et al. Unmet need for clinician engagement regarding financial toxicity after diagnosis of breast cancer. Cancer. 2018;124(18):3668-76. [PMID: 30033631]
39.頭頚部がん患者の小児期の精神的外傷の経験と現在の心理症状との関連
Sarafim-Silva BAM, Duarte GD, Sundefeld M, Biasoli ER, Miyahara GI, Bernabe DG. Childhood trauma is predictive for clinical staging, alcohol consumption, and emotional symptoms in patients with head and neck cancer. Cancer. 2018;124(18):3684-92. [PMID: 30079469]
40.高齢がん患者の総合高齢者評価と予後との関連
Kenis C, Baitar A, Decoster L, De Greve J, Lobelle JP, Flamaing J, et al. The added value of geriatric screening and assessment for predicting overall survival in older patients with cancer. Cancer. 2018;124(18):3753-63. [PMID: 30299540]
41.高齢がん患者の総合高齢者評価や血液検査と予後との関連
Baitar A, Kenis C, Decoster L, De Greve J, Lobelle JP, Flamaing J, et al. The prognostic value of 3 commonly measured blood parameters and geriatric assessment to predict overall survival in addition to clinical information in older patients with cancer. Cancer. 2018;124(18):3764-75. [PMID: 30298906]
42.進行期小児がん患者の倦怠感とその関連要因
Ullrich CK, Dussel V, Orellana L, Kang TI, Rosenberg AR, Feudtner C, et al. Self-reported fatigue in children with advanced cancer: Results of the PediQUEST study. Cancer. 2018;124(18):3776-83. [PMID: 30291811]
43.頭頚部がん患者の自殺リスク
Osazuwa-Peters N, Simpson MC, Zhao L, Boakye EA, Olomukoro SI, Deshields T, et al. Suicide risk among cancer survivors: Head and neck versus other cancers. Cancer. 2018;124(20):4072-9. [PMID: 30335190]
44.AYA世代の若年がん患者の生活の満足度とその関連要因
Leuteritz K, Friedrich M, Sender A, Nowe E, Stoebel-Richter Y, Geue K. Life satisfaction in young adults with cancer and the role of sociodemographic, medical, and psychosocial factors: Results of a longitudinal study. Cancer. 2018;124(22):4374-82. [PMID: 30198085]
45.糖尿病を有する小児がん長期サバイバーの心血管疾患リスク
Winther JF, Bhatia S, Cederkvist L, Gudmundsdottir T, Madanat-Harjuoja L, Tryggvadottir L, et al. Risk of cardiovascular disease among Nordic childhood cancer survivors with diabetes mellitus: A report from adult life after childhood cancer in Scandinavia. Cancer. 2018;124(22):4393-400. [PMID: 30307617]
46.がん治療後1年以内の妊娠での出生児の健康状態とその関連要因
Hartnett KP, Mertens AC, Kramer MR, Lash TL, Spencer JB, Ward KC, et al. Pregnancy after cancer: Does timing of conception affect infant health? Cancer. 2018;124(22):4401-7. [PMID: 30403424]
47.米国のがん患者の1999〜2015年の死亡場所とその関連要因
Chino F, Kamal AH, Leblanc TW, Zafar SY, Suneja G, Chino JP. Place of death for patients with cancer in the United States, 1999 through 2015: Racial, age, and geographic disparities. Cancer. 2018;124(22):4408-19. [PMID: 30343501]

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